Anti-Nidogen/enactin [JF5 (6E4-C9-B7)]

Absolute Antibody

Anti-Nidogen/enactin [JF5 (6E4-C9-B7)]

9

This antribody is specific for the G2 domain of nidogen-1. It binds in such a way that it is able to stop the binding of nidogen to laminin. Nidogen-1 is a sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin.

The binding of the mouse version of this antibody to nidogen-1 was proven by ELISA. Further, high binding affinity of the mouse version of this antibody to nidogen-1 was demonstrated using surface plasmon resonance (Ries et al, 2001; pmid:11589703). To compare nidogen-1 to nidogen-2 in their ability to bind basement membrane components, tissues from embryotic and adult mice were stained using the mouse version of this antibody to be used for immunohistochemistry (Salmivirta et al, 2002; pmid:12243745).

ELISA, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

JF5 (6E4-C9-B7)

Nid1

nidogen 1

A630025O17; enta; entact; entactin; entactin 1; entactin-1; Nid; NID-1; nidog; Nidogen precursor (Entactin); nidogen-1

Rat

IgG2b

Nidogen-1

Mouse

-20°C,2°C to 8°C

12352203