Anti-Nkp46 [29A1.4], Mouse IgG2a, kappa

Absolute Antibody

Anti-Nkp46 [29A1.4], Mouse IgG2a, kappa

9

The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007; PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019; PMID: 31155232).

Flow Cytometry, Other Application

Research Use Only

Monoclonal

29A1.4

Ncr1

natural cytotoxicity triggering receptor 1

Cd335, Ly94, NKp46, natural cytotoxicity triggering receptor 1, MAR1 (mouse activating receptor 1), NK-p46, activating receptor 1, lymphocyte antigen 94, mAR-1, mNKp46, natural killer cell p46-related protein

Mouse

IgG2a

Natural cytotoxicity triggering receptor 1

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse

-20°C,2°C to 8°C

41116161