Anti-NM23 Antibody [13C1]

HUABIO

Anti-NM23 Antibody [13C1]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

13C1

2 mg/ml

Unconjugated

NME1

NME/NM23 nucleoside diphosphate kinase 1

AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, nucleoside diphosphate kinase A, NDP kinase A, epididymis secretory sperm binding protein, granzyme A-activated DNase, metastasis inhibition factor nm23, non-metastatic cells 1, protein (NM23A) expressed in, tumor metastatic process-associated protein

Mouse

IgG1

Nucleoside diphosphate kinase A

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3 end to enhance DNA damage and prevent DNA end reannealing and rapid repair.

Human

Human

-20°C,2°C to 8°C

41116161