Immunohistochemical staining of NMNAT2 using anti-NMNAT2 (human), pAb (Prod. No. AG-25A-0113) in human brain cortex tissue (15microg/ml). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for
Immunohistochemical staining of NMNAT2 using anti-NMNAT2 (human), pAb (Prod. No. AG-25A-0113) in human brain cortex tissue (15microg/ml). This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for
anti-NMNAT2 (human), pAb
AG-25A-0113
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNMNAT2
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-NMNAT2 (human), pAb
- Delivery Days Customer10
- Antibody SpecificityRecognizes human NMNAT2. Detects a band of ~35kDa by Western blot. Not tested in other species.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID23057
- Target nameNMNAT2
- Target descriptionnicotinamide nucleotide adenylyltransferase 2
- Target synonymsC1orf15; NaMN adenylyltransferase 2; nicotinamide mononucleotide adenylyltransferase 2; nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; nicotinate-nucleotide adenylyltransferase 2; NMN adenylyltransferase 2; NMN/NaMN adenylyltransferase 2; PNAT2; pyridine nucleotide adenylyltransferase 2
- HostGuinea Pig
- Protein IDQ9BZQ4
- Protein NameNicotinamide/nicotinic acid mononucleotide adenylyltransferase 2
- Scientific DescriptionNMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimers disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation. - Polyclonal Antibody. Recognizes human NMNAT2. Detects a band of ~35kDa by Western blot. Not tested in other species. Source: Guinea pig. Applications: ELISA, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimers disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203