anti-Nod1 (human), pAb (AL184)

AdipoGen Life Sciences

anti-Nod1 (human), pAb (AL184)

10

Recognizes human Nod1.

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Liquid

Nod1

nucleotide-binding oligomerization domain containing 1

C230079P11; Car; Card4; caspase recruitment domain 4; caspase recruitment domain-containing protein 4; F830007N14Rik; Nl; Nlrc1; nucleotide-binding oligomerization domain-containing protein 1

Rabbit

Nucleotide-binding oligomerization domain-containing protein 1

Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma. - Polyclonal Antibody. Recognizes human Nod1. Source: Rabbit. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma.

Human

-20°C,2°C to 8°C

12352203