Anti-OLR1/LOX1 Rabbit mAb

PTM BIO

Anti-OLR1/LOX1 Rabbit mAb

5

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB, ICC/IF, FC

Research Use Only

Monoclonal

JRMR-10669-30

Unconjugated

Rabbit

IgG

Oxidized low-density lipoprotein receptor 1

This protein is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. It is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. Diseases associated with OLR1 include Myocardial Infarction and Chlamydia Pneumonia. Among its related pathways are Innate Immune System and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and low-density lipoprotein particle receptor activity.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203