anti-OTX2 antibody

Arigo Biolaboratories

anti-OTX2 antibody

23

Western Blot

Research Use Only

Polyclonal

Unconjugated

OTX2

orthodenticle homeobox 2

CPHD6, MCOPS5, homeobox protein OTX2, orthodenticle homolog 2

Rabbit

IgG

This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]

-20°C

12352203