anti-OX40 (human), Rabbit Monoclonal (RM313)

RevMAb Biosciences

anti-OX40 (human), Rabbit Monoclonal (RM313)

10

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

RM313

TNFRSF4

TNF receptor superfamily member 4

ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; lymphoid activation antigene ACT35; OX40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1 receptor; tumor necrosis factor receptor superfamily member 4; TXGP1L

Rabbit

IgG

Tumor necrosis factor receptor superfamily member 4

OX40 receptor is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naive T cells. OX40 is a secondary co-stimulatory immune checkpoint molecule. OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40 expression can promote viral binding and renders cells permissive for viral entry, productive infection and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development. - Recombinant Antibody. This antibody reacts to human OX40 (CD134). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. OX40 receptor is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naive T cells. OX40 is a secondary co-stimulatory immune checkpoint molecule. OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40 expression can promote viral binding and renders cells permissive for viral entry, productive infection and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.

-20°C

12352203