OX40 (human):Fc (human) (rec.)

AdipoGen Life Sciences

OX40 (human):Fc (human) (rec.)

10

Research Use Only

1 mg/ml

>95%

TNFRSF4

TNF receptor superfamily member 4

ACT35, CD134, IMD16, OX40, TXGP1L, tumor necrosis factor receptor superfamily member 4, ACT35 antigen, ATC35 antigen, CD134 antigen, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, lymphoid activation antigene ACT35, tax-transcriptionally activated glycoprotein 1 receptor

Tumor necrosis factor receptor superfamily member 4

OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully. - Protein. Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: 95% (SDS-PAGE). OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.

-20°C,2°C to 8°C

41116100

Human