Anti-p38 alpha / MAPK14 Antibody [SR43-04]

HUABIO

Anti-p38 alpha / MAPK14 Antibody [SR43-04]

7

Flow Cytometry, ImmunoFluorescence, Western Blot

WB,IF-Cell,IF-Tissue

Research Use Only

Monoclonal

SR43-04

1 mg/ml

Unconjugated

MAPK14

mitogen-activated protein kinase 14

CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA, mitogen-activated protein kinase 14, CSAID-binding protein, MAP kinase 14, MAP kinase Mxi2, MAP kinase p38 alpha, MAX-interacting protein 2, cytokine suppressive anti-inflammatory drug binding protein, mitogen-activated protein kinase p38 alpha, p38 MAP kinase, p38 mitogen activated protein kinase, p38alpha Exip, stress-activated protein kinase 2A

Rabbit

IgG

Mitogen-activated protein kinase 14

p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. Persistent activation of the p38 MAPK pathway in muscle satellite cells (muscle stem cells) due to ageing, impairs muscle regeneration. p38 MAP Kinase (MAPK), also called RK or CSBP (Cytokinin Specific Binding Protein), is the mammalian orthologue of the yeast Hog1p MAP kinase, which participates in a signaling cascade controlling cellular responses to cytokines and stress. Four p38 MAP kinases, p38-alpha (MAPK14), -beta (MAPK11), -gamma (MAPK12 / ERK6), and -delta (MAPK13 / SAPK4), have been identified. Similar to the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), ultraviolet light, and growth factors. MKK3 and SEK activate p38 MAP kinase by phosphorylation at Thr-180 and Tyr-182.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161