Anti-p75NTR Rabbit mAb

PTM BIO

Anti-p75NTR Rabbit mAb

5

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF, FC

Research Use Only

Monoclonal

JRMR-10513-71

Unconjugated

Rabbit

IgG

Tumor necrosis factor receptor superfamily member 16

Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Stable for 12 months from date of receipt/reconstitution.

Human, Rat

Human, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203