PDZK3 antibody, N-term

GeneTex

Anti-PAPIN / PDZK3 PAb, N-term

9

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PDZD2

PDZ domain containing 2

activated in prostate cancer protein; AIPC; PAPIN; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZK3; PIN1; plakophilin-related armadillo repeat protein-interactive PDZ protein

Goat

IgG

PDZ domain-containing protein 2

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.

Human

-20°C or -80°C,2°C to 8°C

12352203