Anti-PBX1 Antibody [PSH0-24]
HA721303
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
TargetPBX1
Overview
- SupplierHUABIO
- Product NameAnti-PBX1 Antibody [PSH0-24]
- Delivery Days Customer2
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDPSH0-24
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5087
- Target namePBX1
- Target descriptionPBX homeobox 1
- Target synonymsCAKUHED, pre-B-cell leukemia transcription factor 1, homeobox protein PBX1, homeobox protein PRL, pre-B-cell leukemia homeobox 1
- HostRabbit
- IsotypeIgG
- Protein IDP40424
- Protein NamePre-B-cell leukemia transcription factor 1
- Scientific DescriptionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161