Anti-PCT [PCT Nb3], Camelid VHH, His-tagged,

Absolute Antibody

Anti-PCT [PCT Nb3], Camelid VHH, His-tagged,

9

The antibody is specific for PCT. PCT is a protein consisting of 116 amino acids. PCT is the peptide precursor of calcitonin, a hormone that is synthesized by the parafollicular C cells of the thyroid and involved in calcium homeostasis.

The specificity of the original format of the antibody was confirmed by ELISA analysis (CN104404630A). The binding affinity of the VHH fragment to PCT was measured by surface plasmon resonance (Kd= 8.9 nM). The original format of the antibody was successfully used as a detection antibody, together with anti-PCT Nb2, for the development of a sandwich ELISA for the detection of PCT (Yan et al., 2015; PMID: 25944262).

ELISA, Other Application

Research Use Only

Monoclonal

PCT Nb3

Camel

Human

-20°C,2°C to 8°C

12352203