Anti-PD-L1 [29E.2A3]

Absolute Antibody

Anti-PD-L1 [29E.2A3]

7

The original format of the antibody was able to block the interaction between PD-L1 on the 300.19-hPD-L1 cells and B7-1 on the plate and the interaction between PD-L1 on the 300.19-hPD-L1 cells and PD-1 on the plate (Butte et al., 2008; PMID: 18585785). This antibody was used for detection of PD-L1 expressed in 293T cells by flow cytometry (Broos et al. 2019, PMID: 31394834). The humanized version of the antibody was constructed (AU2019201688). Immunohistochemical staining of frozen tissue sections was performed using the antibody to stain thymic epithelia (Brown et al., 2003; PMID: 12538684).

Flow Cytometry, ImmunoHistoChemistry, Neutralisation/Blocking

FC; blocking; IHC

Research Use Only

Monoclonal

29E.2A3

CD274

CD274 molecule

ADMIO5, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1, programmed cell death 1 ligand 1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1

Human

IgG1

Programmed cell death 1 ligand 1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

-20°C,2°C to 8°C

41116161