Anti-PD-L2 [TY25]

Absolute Antibody

Anti-PD-L2 [TY25]

7

This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.

Flow Cytometry, ImmunoPrecipitation, Western Blot, Neutralisation/Blocking

Fc; IP; WB; Block

Research Use Only

Monoclonal

TY25

Pdcd1lg2

programmed cell death 1 ligand 2

B7-DC, Btdc, F730015O22Rik, PD-L2, programmed cell death 1 ligand 2, PD-1 ligand 2, PDCD1 ligand 2, butyrophilin B7-DC, butyrophilin-like protein, programmed death ligand 2

Mouse

IgG2a

Programmed cell death 1 ligand 2

This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Mouse

This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.

-20°C,2°C to 8°C

12352203