Anti-PDGFR beta Rabbit pAb

PTM BIO

Anti-PDGFR beta Rabbit pAb

5

Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P

Research Use Only

Polyclonal

Unconjugated

Rabbit

IgG

Platelet-derived growth factor receptor beta

PDGF receptor bèta(PDGFRbèta) is a receptor tyrosine kinases, which shares 75% to 85% sequence homology with PDGF receptor alfa. Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to PDGFRalfa and PDGFRbèta. PDGFRbèta homodimers bind PDGF BB and DD isoforms, as well as the PDGF AB heterodimer. The heteromeric PDGF receptor alfa/bèta binds PDGF B, C, and D homodimers, as well as the PDGF AB heterodimer. Various cells differ in the total number of receptors and in the receptor subunit composition, which may account for responsive differences among cell types to PDGF binding.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203