Anti-PDIA6 Mouse mAb

PTM BIO

Anti-PDIA6 Mouse mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB, ICC/IF

Research Use Only

Monoclonal

12940

Unconjugated

Mouse

IgG

Protein disulfide-isomerase A6

May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.

Stable for 12 months from date of receipt/reconstitution.

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203