Anti-PDK2 Rabbit mAb

PTM BIO

Anti-PDK2 Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JRMR-10785-32

Unconjugated

Rabbit

IgG

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2 (PDK2) is a kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via Phosphorylatedrylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. PDK2 Mediates cellular responses to insulin and plays an important role in maintaining normal blood glucose levels and in metabolic adaptation to nutrient availability.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203