Anti-Peroxiredoxin 3 Antibody [JA53-21]

HUABIO

Anti-Peroxiredoxin 3 Antibody [JA53-21]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC,IP

Research Use Only

Monoclonal

JA53-21

1 mg/ml

Unconjugated

PRDX3

peroxiredoxin 3

AOP-1, AOP1, HBC189, MER5, PPPCD, PRO1748, SCAR32, SP-22, prx-III, thioredoxin-dependent peroxide reductase, mitochondrial, antioxidant protein 1, epididymis secretory sperm binding protein, peroxiredoxin III, protein MER5 homolog, thioredoxin-dependent peroxiredoxin 3

Rabbit

IgG

Thioredoxin-dependent peroxide reductase, mitochondrial

Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Human

Human

-20°C,2°C to 8°C

41116161