Anti-Phospho-Histone H3.3 (S31) Antibody [JE62-92]
HA721034
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
TargetH3-3A
Overview
- SupplierHUABIO
- Product NameAnti-Phospho-Histone H3.3 (S31) Antibody [JE62-92]
- Delivery Days Customer2
- ApplicationsImmunoFluorescence, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE62-92
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3020
- Target nameH3-3A
- Target descriptionH3.3 histone A
- Target synonymsBRYLIB1, H3.3A, H3F3, H3F3A, histone H3.3, H3 histone family member 3A, H3 histone, family 3A
- HostRabbit
- IsotypeIgG
- Protein IDP84243
- Protein NameHistone H3.3
- Scientific DescriptionVariant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161