Anti-Phospho-Hormone sensitive lipase (S853) Antibody [SN06-39]
ET1611-19
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLIPE
Overview
- SupplierHUABIO
- Product NameAnti-Phospho-Hormone sensitive lipase (S853) Antibody [SN06-39]
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSN06-39
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3991
- Target nameLIPE
- Target descriptionlipase E, hormone sensitive type
- Target synonymsAOMS4, FPLD6, HSL, LHS, REH, hormone-sensitive lipase, lipase, hormone-sensitive, monoacylglycerol lipase LIPE, retinyl ester hydrolase
- HostRabbit
- IsotypeIgG
- Protein IDQ05469
- Protein NameHormone-sensitive lipase
- Scientific DescriptionHSL (hormone-sensitive lipase), a cytosolic neutral lipase regulated by reversible phosphorylation, catalyzes the rate limiting step in triglyceride lipolysis. HSL hydrolyzes stored triglycerides to free fatty acids in adipose and heart tissues. In organs with steroidogenic tissues, such as small intestine, HSL converts cholesteryl esters to free cholesterol for steroid hormone production. HSL is highly expressed in jejunal enterocytes and in the mucosa of the small intestine. Two major isoforms of HSL have been described resulting from the use of alternative translational start codons. The short isoform is expressed in adipose tissue while the long isoform is expressed in steroidogenic tissues such as testis. The long isoform, often referred to as testicular HSL contains an N-terminus of approximately 300 amino acids not present in the short isoform of HSL.
- ReactivityHuman, Mouse, Rat
- Reactivity SupplierHuman,Mouse,Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161