Anti-Phospho-Hsp27 (S78) Antibody [JJ08-70]

HUABIO

Anti-Phospho-Hsp27 (S78) Antibody [JJ08-70]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,IP

Research Use Only

Monoclonal

JJ08-70

1 mg/ml

Unconjugated

HSPB1

heat shock protein family B (small) member 1

CMT2F, HEL-S-102, HMN2B, HMND3, HS.76067, HSP27, HSP28, Hsp25, SRP27, heat shock protein beta-1, 28 kDa heat shock protein, epididymis secretory protein Li 102, estrogen-regulated 24 kDa protein, heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, heat shock protein family B member 1, stress-responsive protein 27

Rabbit

IgG

Heat shock protein beta-1

Heat shock protein 27 (Hsp27) also known as heat shock protein beta-1 (HSPB1) is a protein that in humans is encoded by the HSPB1 gene. Hsp27 is a chaperone of the sHsp (small heat shock protein) group among alpha-crystallin, Hsp20, and others. The common functions of sHsps are chaperone activity, thermotolerance, inhibition of apoptosis, regulation of cell development, and cell differentiation. They also take part in signal transduction. The main function of Hsp27 is to provide thermotolerance in vivo, cytoprotection, and support of cell survival under stress conditions. A well documented function of Hsp27 is the interaction with actin and intermediate filaments. Another function of Hsp27 is the activation of the proteasome. Probably Hsp27 - among other chaperones - is involved in the process of cell differentiation.

Human

Human

-20°C,2°C to 8°C

41116161