Anti-Phospho-Hsp27 (S82) Antibody [SN06-73]

HUABIO

Anti-Phospho-Hsp27 (S82) Antibody [SN06-73]

7

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot

WB,IP

Research Use Only

Monoclonal

SN06-73

1 mg/ml

Unconjugated

HSPB1

heat shock protein family B (small) member 1

CMT2F, HEL-S-102, HMN2B, HMND3, HS.76067, HSP27, HSP28, Hsp25, SRP27, heat shock protein beta-1, 28 kDa heat shock protein, epididymis secretory protein Li 102, estrogen-regulated 24 kDa protein, heat shock 27 kDa protein, heat shock 27kD protein 1, heat shock 27kDa protein 1, heat shock protein family B member 1, stress-responsive protein 27

Rabbit

IgG

Heat shock protein beta-1

HSP 27 is a constitutively expressed cytoplasmic protein that co-localizes to the nucleus upon stress-induced insult. Heat shock, cytokines and hormones are among the factors that stimulate the synthesis of HSP 27. The intracellular concentration of the mammalian heat shock protein, HSP 27, increases several-fold after heat shock and other metabolic stresses, and is closely associated with the acquisition of thermotolerance. MAP kinase-activated protein kinase-2 phosphorylates HSP 27 on Serine residues Ser 15, Ser 78 and Ser 82, which are phosphorylated in vivo in response to growth factors and heat shock. Ser 15, Ser 78 and Ser 82 occur in the sequence motif RXXS, which is recognized by ribosomal protein S6 kinase II.

Human

Human

Mouse,Rat

-20°C,2°C to 8°C

41116161