Anti-Phospho-IKB alpha (S32) Antibody [ST53-05]

HUABIO

Anti-Phospho-IKB alpha (S32) Antibody [ST53-05]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot

WB,IF-Cell,IP

Research Use Only

Monoclonal

ST53-05

1 mg/ml

Unconjugated

NFKBIA

NFKB inhibitor alpha

EDAID2, IKBA, MAD-3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkappaBalpha, ikB-alpha, major histocompatibility complex enhancer-binding protein MAD3, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Rabbit

IgG

NF-kappa-B inhibitor alpha

On the basis of both functional and structural considerations, members of the IkappaB family of proteins can be divided into four groups. The first of these groups, IkappaB-alpha, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kappaB sites, suggesting that the IkappaB-alpha family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkappaB family is represented by a protein designated IkappaB-beta. The third group of IkappaB proteins is represented by IkappaB-gamma, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IkappaB family member, IkappaB-epsilon, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel.

Human, Mouse

Human,Mouse

-20°C,2°C to 8°C

41116161