Anti-Phospho-PKC zeta (T560) Antibody [SN0753]

HUABIO

Anti-Phospho-PKC zeta (T560) Antibody [SN0753]

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Monoclonal

SN0753

1 mg/ml

Unconjugated

PRKCZ

protein kinase C zeta

PKC-ZETA, PKC2, protein kinase C zeta type, nPKC-zeta

Rabbit

IgG

Protein kinase C zeta type

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into many different isoforms (alpha, betaI, betaII, gamma, delta, epsilon, omega, h, theta, lambda/iota, ? and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC delta and epsilon are independent of Ca++. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161