Immunohistochemical staining of formalin fixed and paraffin embedded human cerebral cortex tissue sections using Anti-phospho-Rsk1 (Thr359/Ser363) RM233 at a 1:200 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human cerebral cortex tissue sections using Anti-phospho-Rsk1 (Thr359/Ser363) RM233 at a 1:200 dilution.
anti-Phospho-Rsk1 (Thr359/Ser363) (human), Rabbit Monoclonal (RM233)
REV-31-1117-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRPS6KA1
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-Phospho-Rsk1 (Thr359/Ser363) (human), Rabbit Monoclonal (RM233)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts to human RSK1 only when phosphorylated at Thr359/Ser363.
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM233
- FormulationLiquid
- Gene ID6195
- Target nameRPS6KA1
- Target descriptionribosomal protein S6 kinase A1
- Target synonyms90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK1; MAPKAPK1A; MAPKAPK-1a; p90Rsk; p90-RSK 1; p90RSK1; p90S6K; ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal S6 kinase 1; RSK; RSK1; RSK-1; S6K-alpha 1
- HostRabbit
- IsotypeIgG
- Protein IDQ15418
- Protein NameRibosomal protein S6 kinase alpha-1
- Scientific DescriptionRecombinant Antibody. This antibody reacts to human RSK1 only when phosphorylated at Thr359/Ser363. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363 and Thr573, are important for kinase activation. RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters. Evidence from animal models suggests that RSK1 is a key regulator of glucose homeostasis and cell size. - The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363 and Thr573, are important for kinase activation. RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters. Evidence from animal models suggests that RSK1 is a key regulator of glucose homeostasis and cell size.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203