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Anti-Phosphorylated-AKT (Thr308) Rabbit mAb

PTM-6735
PTM BIO
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
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Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Phosphorylated-AKT (Thr308) Rabbit mAb
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Applications Supplier
    WB
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JMMR-3567
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP31751
  • Protein Name
    RAC-beta serine/threonine-protein kinase
  • Scientific Description
    Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then Phosphorylatedrylates and inactivates components of the apoptotic machinery. Phosphorylatedrylation on Thr-308, Ser-473 and Tyr-474 of AKT are required for its full activity. AKT1 Thr-308 and Ser-473 is Phosphorylatedrylated by IKBKE and TBK1.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity
    Mouse
  • Reactivity Supplier
    Mouse
  • Reactivity Supplier Note
    Protein A purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203