Anti-Phosphorylated-PTP1B (Ser386) Rabbit mAb

PTM BIO

Anti-Phosphorylated-PTP1B (Ser386) Rabbit mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB, ICC/IF

Research Use Only

Monoclonal

PA-120 - 131

Unconjugated

Rabbit

IgG

Tyrosine-protein phosphatase non-receptor type 1

Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dePhosphorylatedrylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dePhosphorylatedrylation of MET.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203