Anti-Phosphorylated-Tau (Ser262) Rabbit mAb

PTM BIO

Anti-Phosphorylated-Tau (Ser262) Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JRMR-10078-28

Unconjugated

Rabbit

IgG

Microtubule-associated protein tau

Tau is a neuronal microtubule-associated protein, which is mainly located in the cytoplasm, cytoskeleton and cell membrane. Tau is expressed in neuronal tissues and exists in the form of a variety of alternate splicing subtypes. Its C-terminus is combined with axon microtubules, and the N-terminus is combined with neuroplasmic membrane components to maintain the stability and plasticity of the neuronal cytoskeleton. In neurons, hyperPhosphorylatedrylated and abnormally glycosylated Tau protein accumulates, causing neurofibrosis and neurodegeneration, such as Alzheimer’s disease (AD), frontotemporal dementia, and chronic traumatic encephalopathy (CTE), Parkinson's disease after encephalitis, etc.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203