Anti-PI3 Kinase p110 delta Rabbit mAb

PTM BIO

Anti-PI3 Kinase p110 delta Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JRMR-10545-71

Unconjugated

Rabbit

IgG

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) belongs to Class I Phosphorylatedinositide-3-kinase (PI3K) which Phosphorylatedrylates phosphatidylinositol (PI) and its Phosphorylatedrylated derivatives at position 3 of the inositol ring to produce 3-Phosphorylatedinositides and uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203