Anti-PKC delta Antibody [JJ093-02]

HUABIO

Anti-PKC delta Antibody [JJ093-02]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P

Research Use Only

Monoclonal

JJ093-02

1 mg/ml

Unconjugated

PRKCD

protein kinase C delta

ALPS3, CVID9, MAY1, PKCD, nPKC-delta, protein kinase C delta type, protein kinase C delta VIII, tyrosine-protein kinase PRKCD

Rabbit

IgG

Protein kinase C delta type

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, epsilon, aeta, eta, theta, lambda/iota, micro and nu). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC delta and epsilon are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161