Anti-PLOD3

Applied Biological Materials

Anti-PLOD3

9

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Rabbit

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]

-20°C,2°C to 8°C

12352203