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anti-Podoplanin (gp36), Rabbit Monoclonal (RM449)

anti-Podoplanin (gp36), Rabbit Monoclonal (RM449)

Research Use Only
REV-31-1341-00
RevMAb Biosciences
ApplicationsWestern Blot, ImmunoHistoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetPDPN
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-Podoplanin (gp36), Rabbit Monoclonal (RM449)
  • Delivery Days Customer
    5
  • Antibody Specificity
    This antibody reacts to human podoplanin (Gp36).
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM449
  • Formulation
    Liquid
  • Gene ID10630
  • Target name
    PDPN
  • Target description
    podoplanin
  • Target synonyms
    AGGRUS; glycoprotein 36; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); OTS8; PA2.26; PA2.26 antigen; podoplanin; T1A; T1A2; T1A-2; T1-alpha; TI1A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ86YL7
  • Protein Name
    Podoplanin
  • Scientific Description
    Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. - Recombinant Antibody. This antibody reacts to human podoplanin (Gp36). Applications: IHC, WB. Clone: RM449. Isotype: Rabbit IgG. Formulation: Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203