Anti-PP2A(alpha+beta) Antibody

HUABIO

Anti-PP2A(alpha+beta) Antibody

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PPP2CA

protein phosphatase 2 catalytic subunit alpha

HJS3, NEDLBA, PP2Ac, PP2CA, PP2Calpha, RP-C, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, protein phosphatase 2, catalytic subunit, alpha isozyme, replication protein C

Rabbit

IgG

Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A? and PP2A. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A-alpha and -A-beta, PP2A-B-alpha and -B-beta, PP2A-C-alpha and -C-beta, PP2A-B56-alpha and -B56-beta.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161