Anti-pp60Src [GD11]

Absolute Antibody

Anti-pp60Src [GD11]

7

This antibody is specific for pp60src. It recognizes this protein in avians, humans and different rodents. It recognizes amino acids 82-169. Pp60src is a non-receptor protein tyrosine kinase which is activated following engagement of many different classe

To confirm wether a 60,000-Mr phosphoprotein was pp60src, an immunoprecipitation was preformed using the mouse version of this antibody. Furthermore, PrARSV-infected CE cells were immunostained using this antibody (Parsons et al, 1984; pmid:6205164). To determine wether pp60src is present in human T cells, an immunoprecipitation and subsequent western blot were preformed using the mouse version of this antibody on human T cell cultures (Branch and Mills, 1995; pmid:7535811). Proteins from fetal rat lung cells were immunoblotted using the mouse version of this antibody (Liu et al, 1996; pmid:8636139). While researching store-mediated Ca2+ entry, a western blot was preformed on human blood cells using the mouse version of this antibody (Redondo et al, 2005; pmid:15894173).

ImmunoFluorescence, ImmunoPrecipitation, Western Blot

WB; IP; IF

Research Use Only

Monoclonal

GD11

SRC

SRC proto-oncogene, non-receptor tyrosine kinase

c-src; c-src protein, C terminus; non-tyrosine protein kinase; p60-Src; PP60C-SCR; pp60c-src; proto-oncogene c-Src; proto-oncogene tyrosine-protein kinase Src; SDR; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene

Rabbit

IgG

Proto-oncogene tyrosine-protein kinase Src

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Avian, Human, Mink, Mouse, Rat

Mink, Rat, Human, Mouse, Birds

The mouse version of this antibody was generated by immunizing a mouse with recombinant chicken pp60src.

-20°C,2°C to 8°C

12352203