Anti-PPP1CB Rabbit mAb

PTM BIO

Anti-PPP1CB Rabbit mAb

5

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry Paraffin

WB, IHC-P, ICC/IF, FC, IP

Research Use Only

Monoclonal

JRMR-10592-10

Unconjugated

Rabbit

IgG

Serine/threonine-protein phosphatase PP1-beta catalytic subunit

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dePhosphorylatedrylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 Phosphorylatedrylation. May dePhosphorylatedrylate CSNK1D and CSNK1E. DePhosphorylatedrylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203