Anti-PPP1R1A Antibody [SN0756]

HUABIO

Anti-PPP1R1A Antibody [SN0756]

7

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC,IP

Research Use Only

Monoclonal

SN0756

1 mg/ml

Unconjugated

PPP1R1A

protein phosphatase 1 regulatory inhibitor subunit 1A

I1, IPP1, protein phosphatase 1 regulatory subunit 1A, I-1, IPP-1, inhibitor-1, protein phosphatase inhibitor-1

Rabbit

IgG

Protein phosphatase 1 regulatory subunit 1A

The inhibitor of protein phosphatase 1 (IPP-1, I-1) plays a role in regulating the phosphorylation of other proteins, and is itself phosphorylated by a cyclic AMP-dependent protein kinase. IPP-1 is present in skeletal muscles and in distinct neuronal systems of the brain. The localization and expression of IPP-1 suggests that it may play discrete roles in certain regions and developing stages of the brain, independent of the regulation of protein phosphatase type 1 (PP-1). PP-1 binds to both phosphorylated and dephosphorylated IPP-1. Conversion of PP-1 to an Mn2+-dependent state appears to play a role in its regulation by IPP-1. IPP-1 attenuates the activity of glycogen phosphorylase and is thought to play an important role in the hormonal control of glycogen metabolism.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161