Anti-PPP6C Antibody [JE61-21]

HUABIO

Anti-PPP6C Antibody [JE61-21]

2

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE61-21

1 mg/ml

Unconjugated

PPP6C

protein phosphatase 6 catalytic subunit

PP6, PP6C, serine/threonine-protein phosphatase 6 catalytic subunit, serine/threonine protein phosphatase catalytic subunit

Rabbit

IgG

Serine/threonine-protein phosphatase 6 catalytic subunit

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX, is a putative member of a novel PP family. PP6, also known as PPP6C, is a 305 amino acid cytoplasmic protein that belongs to the PPP phosphatase family. Ubiquitously expressed, PP6 is component of a signaling pathway regulating cell cycle progression in response to IL-2 receptor stimulation and is involved in suppressing inflammatory responses by specifically down-regulating TR4.

-20°C,2°C to 8°C

41116161