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Western blot analysis using anti-Progranulin (human), pAb (Prod. No. AG-25A-0112) at 1:2000 dilution. 1: Human Progranulin (FLAG®-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (FLAG®
Western blot analysis using anti-Progranulin (human), pAb (Prod. No. AG-25A-0112) at 1:2000 dilution. 1: Human Progranulin (FLAG®-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (FLAG®
Western blot analysis using anti-Progranulin (human), pAb (Prod. No. AG-25A-0112) at 1:2000 dilution. 1: Human Progranulin (FLAG®-tagged) (50ng). 2: Human Progranulin (tag-free) (100ng). 3: Human Granulin C (FLAG®

anti-Progranulin (human), pAb

Research Use Only
AG-25A-0112
AdipoGen Life Sciences
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetGRN
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Progranulin (human), pAb
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human progranulin. Detects a band of ~90kDa by Western blot. Weakly cross-reacts with mouse progranulin. Cross-reacts with hGRN-C and hGRN-F.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Gene ID2896
  • Target name
    GRN
  • Target description
    granulin precursor
  • Target synonyms
    acrogranin; CLN11; epithelin; GEP; glycoprotein 88; glycoprotein of 88 Kda; GP88; granulin-epithelin; granulins; PC cell-derived growth factor; PCDGF; PEPI; PGRN; proepithelin; progranulin
  • Host
    Guinea Pig
  • Scientific Description
    Polyclonal Antibody. Recognizes human progranulin. Detects a band of ~90kDa by Western blot. Weakly cross-reacts with mouse progranulin. Cross-reacts with hGRN-C and hGRN-F. Source: Guinea pig. Applications: ELISA, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimers Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. - Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimers Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203