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Anti-Propionyl-Histone H3 (Lys14) Rabbit pAb

Name: Anti-Propionyl-Histone H3 (Lys14) Rabbit pAb
SKU: PTM-211_P78
Availability: BackOrder

PTM-211

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman, Mouse, Rat

Overview

Supplier
PTM BIO
Product Name
Anti-Propionyl-Histone H3 (Lys14) Rabbit pAb
Delivery Days Customer
5
Applications
Western Blot
Applications Supplier
WB
Category Supplier
Antibody
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Host
Rabbit
Isotype
IgG
Protein IDP68431
Protein Name
Histone H3.1
Scientific Description
Histones are subject to a variety of enzyme catalyzed modifications, including acetylation, methylation, Phosphorylatedrylation, ubiquitylation, etc. Lysine propionylation (Kprop) is structurally similar to lysine acetylation, is a newly identified reversible modification controlling protein activity. Lysine propionylation is abundant in both prokaryotes and eukaryotes and has been found in wide ranges of proteins, including histones and non-histone substrates, such as p53. Similar to acetylation of histone H3 at Lys12, propionylation of histone H3 at Lys14 may play a vital role in the epigenetic modulation, including chromatin remodeling and transcriptional regulation.
Shelf life instruction
Stable for 12 months from date of receipt/reconstitution.
Reactivity
Human, Mouse, Rat
Reactivity Supplier
Human, Mouse, Rat
Reactivity Supplier Note
Protein A purified
Storage Instruction
Store at -20°C. Avoid freeze/thaw cycles.
UNSPSC
12352203

Kezhi Yan, et al. 'Deficient histone H3 propionylation by BRPF1-KAT6 complexes in neurodevelopmental disorders and cancer' Science Advances (2020)
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