Anti-PYK2 Antibody [SC06-15]

HUABIO

Anti-PYK2 Antibody [SC06-15]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P

Research Use Only

Monoclonal

SC06-15

1 mg/ml

Unconjugated

PTK2B

protein tyrosine kinase 2 beta

CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, protein-tyrosine kinase 2-beta, CAK-beta, FADK 2, PTK2B protein tyrosine kinase 2 beta, calcium-dependent tyrosine kinase, calcium-regulated non-receptor proline-rich tyrosine kinase, cell adhesion kinase beta, focal adhesion kinase 2, proline-rich tyrosine kinase 2, protein kinase B, related adhesion focal tyrosine kinase

Rabbit

IgG

Protein-tyrosine kinase 2-beta

This gene encodes a cytoplasmic protein tyrosine kinase that is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. In addition, SOCE-induced Pyk2 activation mediates disassembly of endothelial adherens junctions, via tyrosine (Y1981-residue) phosphorylation of VE-PTP.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161