Anti-Rabies Virus Glycoprotein [R16E5]

Absolute Antibody

Anti-Rabies Virus Glycoprotein [R16E5]

9

This antibody recognizes and binds the antigenic site III of the rabies virus glycoprotein. However, it is not capable of binding the CVS-BHK strain of the rabies virus.

This antibody successfully binds and neutralizes the rabies virus glycoprotein of the PV, CVS-11, SAD and Flury LEP strains. It does not bind the CVS-BHK strain. The binding specificity of the antibody for rabies virus glycoprotein was confirmed with ELISA and western blotting. This antibody in combination with another murine anti-rabies antibody M5B4 was used in the preparation of a diabody D06 (PMID: 20573881).

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

R16E5

Canine

IgG2

Glycoprotein

This chimeric dog antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203