Anti-RALBP1 Antibody [SC06-49]

HUABIO

Anti-RALBP1 Antibody [SC06-49]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

SC06-49

1 mg/ml

Unconjugated

RALBP1

ralA binding protein 1

RIP1, RLIP1, RLIP76, ralA-binding protein 1, 76 kDa Ral-interacting protein, DNP-SG ATPase, dinitrophenyl S-glutathione ATPase, ral-interacting protein 1

Rabbit

IgG

RalA-binding protein 1

Ral A and Ral B constitute a distinct subfamily of Ras-related GTPases (i.e., GDP/GTP binding proteins). Ral proteins are activated by a unique nucleotide exchange factor, Ral GDS, and deactivated by a distinct GTPase-activating protein. Unlike Ras proteins, Ral A and Ral B fail to induce transformed foci when activated variants are expressed in various recipient cells. A potential downstream target of Ral, designated Ral BP-1, has been shown to contain a Rho-GTPase-activating domain. This Rho-GTPase-activating domain interacts preferentially with the Rho family member Cdc42. A Ras/Ral signaling pathway has been reported to mediate phospholipase D (PLD) activation by v-Src, thus indicating PLD as another downstream target of Ral A.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161