Anti-RANK-L [WBP114_7.80]

Absolute Antibody

Anti-RANK-L [WBP114_7.80]

9

The specificity of the original format of the antibody to human RANKL was confirmed by ELISA analysis (EC50= 0.12 nM). The antibody could block the RANKL binding to RANK (IC50 = 0.22 nM). The original format of the antibody could inhibit the RANKL-inducible luciferase activity (IC50 = 1.04 nM). The binding affinity of the original format of the antibody to RANKL was measured by surface plasmon resonance (Kd= 60 pM) (WO2019080909).

ELISA, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

WBP114_7.80

TNFSF11

TNF superfamily member 11

CD254, ODF, OPGL, OPTB2, RANKL, TNLG6B, TRANCE, hRANKL2, sOdf, tumor necrosis factor ligand superfamily member 11, TNF-related activation-induced cytokine, osteoclast differentiation factor, osteoprotegerin ligand, receptor activator of nuclear factor kappa B ligand, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand 6B, tumor necrosis factor superfamily member 11

Human

IgG1

Tumor necrosis factor ligand superfamily member 11

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203