Anti-RAP1A + RAP1B Rabbit mAb

PTM BIO

Anti-RAP1A + RAP1B Rabbit mAb

5

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

WB, ICC/IF, IP

Research Use Only

Monoclonal

JRMR-10772-60

Unconjugated

Rabbit

IgG

Ras-related protein Rap-1A

Rap1 is a member of the Ras family of small GTPases. It undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of Rap1 is therefore affected by the balance of intracellular levels of GEFs and GAPs. This protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203