Anti-Raptor Antibody

HUABIO

Anti-Raptor Antibody

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

RPTOR

regulatory associated protein of MTOR complex 1

KOG1, Mip1, regulatory-associated protein of mTOR, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, raptor

Rabbit

IgG

Regulatory-associated protein of mTOR

Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161