Anti-ribosomal P protein [B10]

Absolute Antibody

Anti-ribosomal P protein [B10]

9

This antibody recognises DDxGF sequence of the C-terminal of eukaryotic ribosomal P proteins.

Both B10 mAb and scFv were demonstrated to detect eukaryote ribosomal P proteins with a high specificity demonstrated by the alanine-scanning mutagenesis of peptide R13 (Lopez Bergami et al., 2003). Consequently, this antibody can be used in the detection of ribosomal P proteins in various eukarote tissues. Finally, anti-P protein antibodies are observed in certain pathologies, such as Trypanosoma cruzi infection and SLE, and thus B10 antibody might be utilised as a model for the investigation of the immunology of these diseases (Lopez Bergami et al., 2003).

Functional Assay

Research Use Only

Monoclonal

B10

Mouse

IgG1

This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Parasite

-20°C,2°C to 8°C

12352203