Anti-RNase A [cAb-RN05]

Absolute Antibody

Anti-RNase A [cAb-RN05]

9

This antibody binds bovine RNase A. RNase A is an endonuclease enzyme that catalyzes the cleavage of RNA on the 3 side of pyrimidine nucleotides. It acts on single-stranded and double-stranded RNA.

This antibody binds bovine RNase with an affinity in the picomolar range. This affinity matured version of VHH antibody cAb-RN05 binds bovine RNase with an affinity of Kd= 180 pM (PMID: 17888451). 5-3 cUMP that binds into the active site of RNase A does not compete with cAb-RN05 for binding to RNase A in an ELISA (PMID: 10196124).

ELISA

Research Use Only

Monoclonal

cAb-RN05

RNASE1

ribonuclease, RNase A family, 1 (pancreatic)

ribonuclease A (pancreatic); ribonuclease pancreatic; RNase 1; RNase A; RNS1

Rabbit

IgG

Ribonuclease pancreatic

Bovine

-20°C,2°C to 8°C

12352203