Anti-ROCK1 Mouse mAb

PTM BIO

Anti-ROCK1 Mouse mAb

5

Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P

Research Use Only

Monoclonal

JMMR-2495

Unconjugated

Mouse

IgG

Rho-associated protein kinase 1

ROCK1 is a protein serine/threonine kinase, also known as rho-associated, coiled-coil-containing protein kinase 1. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. ROCK1 plays a role in cancer and in particular cell motility, metastasis, and angiogenesis. ROCK1 is also a key regulator of actin-myosin contraction, stability, and cell polarity.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse, Rat

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203